Publications by authors named "S Zanon"
Article Synopsis
- - The study investigates the impact of Diffuse Idiopathic Skeletal Hyperostosis (DISH) on the risk of Coronary Artery Disease (CAD), finding a significant association between DISH and higher CAD complexity.
- - Researchers analyzed data from 187 patients, identifying that 44.4% had DISH, which correlated with increased SYNTAX scores, indicating more severe CAD, independent of traditional risk factors.
- - Specifically, patients under 70 years with DISH had a sevenfold increased risk of severe CAD (SYNTAX score ≥34), suggesting that DISH could serve as a risk marker in cardiovascular assessments.
Coronary physiology assessments: historical overview and future challenges.
Minerva Cardiol Angiol
May 2024
Coronary physiological assessment has garnered extensive application in managing patients with coronary artery disease, encompassing both acute and chronic scenarios. Beyond the historical purpose as tool to define the hemodynamic significance of a given artery lesion, coronary artery physiology allows for a complete investigation of epicardial and microvascular circulation. The longitudinal assessment of the distribution pattern of coronary disease based on pressure wire technology provides crucial information to define the best management and procedural planning.
View Article and Find Full Text PDF#FullPhysiology is a comprehensive and systematic approach to evaluate patients with suspected coronary disease using PressureWire technology (Abbott Vascular, Santa Clara, CA, USA). This advancement in technology enables the investigation of each component of the coronary circulation, including epicardial, microvascular, and vasomotor function, without significantly increasing procedural time or technical complexity. By identifying the predominant physiopathology responsible for myocardial ischemia, #FullPhysiology enhances precision medicine by providing accurate diagnosis and facilitating tailored interventional or medical treatments.
View Article and Find Full Text PDFElectrical storm is a medical emergency characterized by ventricular arrythmia recurrence that can lead to hemodynamic instability. The incidence of this clinical condition is rising, mainly in implantable cardioverter defibrillator patients, and its prognosis is often poor. Early acknowledgment, management and treatment have a key role in reducing mortality in the acute phase and improving the quality of life of these patients.
View Article and Find Full Text PDFBackground: Physical exercise can improve synaptic function and protect the nervous system against many diseases by altering gene regulation. MicroRNAs (miRs) have emerged as vital regulators of gene expression and protein synthesis not only in the muscular system, but also in the brain.
Objective: Here we investigated whether exercise-induced miRs expression in the nervous and muscular systems is activity-dependent or it remains regulated even after exercise cessation.