Publications by authors named "S Zanati"
Cardiotoxicity is the serious side effect of doxorubicin treatment. Ceramides are formed from the degradation of sphingolipids in cell membranes and play an important role in signaling and modulating biological processes. There is evidence that omega-3 fatty acid administration can act on this pathway.
View Article and Find Full Text PDFArticle Synopsis
- Endoscopic submucosal dissection (ESD) is being considered for treating large nonpedunculated colorectal polyps (LNPCPs) to manage potential low-risk cancers, but its effectiveness in the right colon is unclear.
- A study analyzed over 3,000 cases, finding that only 2.6% of patients who underwent endoscopic resection (ER) had cancers, with just 0.78% being classified as low-risk.
- The results suggest that a universal ESD approach for right colon LNPCPs may not significantly improve patient outcomes due to the low prevalence of treatable low-risk cancers.
Unlabelled: Cardiovascular disease is a leading cause of death worldwide. Heart failure is a cardiovascular disease with high prevalence, morbidity, and mortality. Several natural compounds have been studied for attenuating pathological cardiac remodeling.
View Article and Find Full Text PDFObjective: Management of covert submucosal invasive cancer (SMIC) discovered after piecemeal endoscopic mucosal resection (pEMR) of large (>20 mm) non-pedunculated colorectal polyps is challenging. The residual cancer risk is largely unknown. We sought to evaluate this in a large tertiary referral cohort.
View Article and Find Full Text PDFAssociation between frailty and C-terminal agrin fragment with 3-month mortality following ST-elevation myocardial infarction.
Exp Gerontol
February 2022
Article Synopsis
- - The study aimed to assess the link between frailty (using the Clinical Frailty Scale and FRAIL scale) and C-terminal agrin fragment levels with 3-month mortality in patients who experienced a ST-segment elevation myocardial infarction (STEMI).
- - It included 111 patients averaging 62.3 years old, where 11.7% died within 3 months post-discharge; frailty assessments revealed most were not frail based on CFS and FRAIL scale classifications.
- - The results indicated that higher frailty (as per CFS) and lower CAF levels were significantly associated with increased 3-month mortality, particularly in patients aged 65 and older.