Publications by authors named "S Zakynthinos"
Background: Noninvasive ventilation (NIV) has been the cornerstone for managing acute exacerbations of COPD (AECOPD) with hypercapnic respiratory failure. Nasal high flow (NHF) oxygen therapy has emerged as a potential alternative, offering a more tolerable modality with promising outcomes. The aim of the present study was to evaluate whether NHF respiratory support is noninferior to NIV with respect to treatment failure, in patients with mild-to-moderate hypercapnic AECOPD.
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- Post-COVID-19 syndrome affects millions, and while rehabilitation is important, studies show mixed results due to variations in participant characteristics and factors like age and disease severity that are not well understood.
- This non-randomized case-control study involved participants with post-COVID-19 symptoms, comparing those who attended an 8-week supervised rehabilitation program to those who did not, with measurements taken at the start and after the program.
- Results indicated that participants in rehabilitation showed significant improvements in various health metrics, including walking distance, physical performance, quality of life, and cognitive function, further highlighting the potential benefits of rehabilitation for post-COVID-19 recovery.
Background: The aim of this study was to investigate the effect of normal breath and apnea swimming on acid-base balance, physiological responses and performance during high-intensity interval training in swimming.
Methods: Sixteen swimmers completed 6×50 m intervals of freestyle swimming with normal breath and apnea at maximum intensity, with 1 minute rest. Capillary blood gases (pH, PCO
The effect of high-flow oxygen via tracheostomy on respiratory pattern and diaphragmatic function in patients with prolonged mechanical ventilation: A randomized, physiological, crossover study.
J Intensive Med
April 2024
Background: Compared to conventional oxygen devices, high-flow oxygen treatment (HFOT) through the nasal cannulae has demonstrated clinical benefits. Limited data exist on whether such effects are also present in HFOT through tracheostomy. Hence, we aimed to examine the short-term effects of HFOT through tracheostomy on diaphragmatic function and respiratory parameters in tracheostomized patients on prolonged mechanical ventilation.
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- The study explores the relationship between the venous excess ultrasound (VExUS) score and major adverse kidney events (MAKE30) in ICU patients, focusing on changes in the VExUS score over the first three days after admission.
- A prospective observational study included 89 patients, revealing that a change in VExUS score (D-VExUS) was linked to adverse kidney events and mortality within 30 days, while individual VExUS scores did not show this association.
- The findings suggest that monitoring the early trajectory of VExUS score can provide better insights into patient outcomes compared to isolated measurements at specific time points.