Co-selection of antibiotic and disinfectant resistance in environmental bacteria: Health implications and mitigation strategies.

Background: The rapid emergence of co-selection between antimicrobials, including antibiotics and disinfectants, presents a significant challenge to healthcare systems. This phenomenon exacerbates contamination risks and limits the effectiveness of strategies to combat antibiotic resistance in clinical settings. This study aimed to investigate the prevalence and characteristics of bacteria in hospital environments that exhibit co-selection mechanisms and their potential implications for patient health, framed within the One Health perspective.

The effect of fabrication procedures and thermomechanical loading on the structural properties of screw-retained metal-ceramic implant restorations: An in vitro study.

Purpose: Metal-ceramic screw-retained implant restorations persist as a fundamental choice in specific clinical scenarios. Little is known about the effects of fabrication steps and aging on their structural properties. This study aimed to investigate how laboratory fabrication procedures and thermomechanical loading affect the structural properties of screw-retained metal-ceramic implant restorations.

Are There Clinical Differences Between 3D-Printed and Milled Complete Dentures? A Systematic Review and Meta-analysis.

Limited studies assess clinical key factors in the success of digitally fabricated complete dentures between additive and subtractive methods. This study aimed to compare 2 determinants of clinical success-retention and patient satisfaction- in complete dentures fabricated using additive and subtractive approaches. PubMed, Scopus, Web of Science, Embase, Cochrane Library, and Google Scholar were searched up to August 2024.

Activation of muscle amine functional groups using eutectic mixture to enhance tissue adhesiveness of injectable, conductive and therapeutic granular hydrogel for diabetic ulcer regeneration.

Herein, Polydopamine-modified microgels and microgels incorporated with superficial epoxy groups were synthesized and applied as precursors for the fabrication of four granular hydrogels. To enhance the tissue adhesiveness, a ternary deep eutectic solvent was synthesized to activate the muscle amine functional groups facilitating the formation of robust NC bonds at ambient conditions. At a certain shear rate of 10 s, hydrogel DMG displayed a viscosity of 9×10 Pa/s, representing the highest complex viscosity among the tested hydrogels primarily driven by quinone groups in PDA which enhanced reversible interactions, thereby increasing particle cohesion.

Fungal presence and health implications in hospital water systems.

Given the increasing occurrence of invasive fungal infections and the limited efficacy of modern antifungal medications, it is crucial to disseminate information regarding the potential sources of nosocomial mycoses through the One Health approach. This study investigated the presence and antifungal susceptibility of fungi in biofilm and water samples obtained from the drinking water distribution system (DWDS) of hospitals. The positivity rate for fungi in biofilm and water samples was 41% and 9%, respectively, with species, a significant causative agent of nosocomial mycoses, being the predominant fungi identified.