Pharmacokinetics of cyclosporine as a function of energy--protein deficiency in children with chronic renal failure.

The present study was conducted to determine whether malnutrition in patients with chronic renal failure requiring cyclosporine therapy for renal transplantation has some effect on the clinical pharmacokinetics of cyclosporine. Eleven pediatric patients were enrolled in this study before renal transplantation and divided into two groups (group I: six well-nourished patients with a deficit in weight/height ratio < or = 7%; group II: five malnourished patients with a deficit in weight/height > 8%). The patients received a single oral dose of cyclosporine (3.

[Chemico-clinical permanent program of the NIH. I. The first phase of the program].

Background Information: This is the report of the first phase of an internal/external permanent program of the MNIH (Mexican National Institutes of Health). The permanent program evolved from a previous one operating from 1984 to 1988 in the MNIH (Refs 1-5).

Objective: To evaluate the precision of the assay systems used currently by the clinical chemistry laboratories of the MNIH.

Idiopathic gastroparesis in patients with unexplained nausea and vomiting.

Nausea and vomiting are symptoms sometimes associated with motor dysfunction. We compared a group of young patients suffering from chronic nausea and/or vomiting and normal upper gastrointestinal x-ray series with a control group. The members of both groups underwent isotopic examinations of their stomachs.