Publications by authors named "S Z Trooskin"
Introduction: The 2015 American Thyroid Association guidelines recommend lymph node mapping US in patients with definitive cytological evidence of thyroid cancer. Suspicious lymph node features on imaging including enlarged size (>1 cm in any dimension), architectural distortion, loss of fatty hilum, and microcalcifications often prompt evaluation with fine needle aspiration. There is no universally agreed upon model for determining which ultrasound characteristics most strongly correlate with metastatic disease.
View Article and Find Full Text PDFBackground: Differentiated thyroid cancer (DTC) affects thousands of lives worldwide each year. Typically, DTC is a treatable disease with a good prognosis. Yet, some patients are subjected to partial or total thyroidectomy and radioiodine therapy to prevent local disease recurrence and metastasis.
View Article and Find Full Text PDFArticle Synopsis
- - Differentiated thyroid cancer (DTC) is generally treatable, but some patients undergo aggressive treatments like thyroidectomy and radioiodine therapy, which can negatively impact their quality of life and may not be necessary for less aggressive cases.
- - A new multi-omics model has been proposed to better diagnose DTC by differentiating between normal thyroid tissue and tumors, particularly in papillary thyroid cancer (PTC), by analyzing various biological markers.
- - The study suggests that analyzing DNA mutations, telomere length, and metabolic profiles of thyroid tissues could lead to more effective patient management and avoid unnecessary treatments through targeted molecular approaches.
Background: Intraoperative parathyroid hormone (IOPTH) testing facilitates focused parathyroidectomy to establish biochemical cure but may be time-consuming. A dedicated immunoassay machine was relocated to the operating room for IOPTH. These data seek to determine association of operating room-based IOPTH with operative time, laboratory turnaround time (TAT), and cost.
View Article and Find Full Text PDFBackground: Periodic surveillance of the hepatitis C virus (HCV) care cascade is important for tracking progress toward HCV elimination goals, identifying gaps in care, and prioritizing resource allocation. In the pre-direct-acting antiviral (DAA) era, it was estimated that 50% of HCV-infected individuals were diagnosed and that 16% had been prescribed interferon-based therapy. Since then, few studies utilizing nationally representative data from the DAA era have been conducted in the United States.
View Article and Find Full Text PDF