Publications by authors named "S Zırh"
Article Synopsis
- The Hedgehog signaling pathway is important for folliculogenesis, but its relationship with FF-MAS oxysterol in this process, especially in conditions like PCOS, is not well understood.
- *The study found that FF-MAS enhances the proliferation of granulosa cells (GCs) and increases key Hedgehog pathway components (SMO and Gli1) even in the presence of an inhibitor, suggesting its significant role in follicular development.
- *Ultimately, this research could lead to new strategies for improving human IVF treatments by leveraging FF-MAS's effects on GCs and folliculogenesis.
Background: Traumatic spinal cord injury (SCI) is the most common preventable cause of morbidity. Despite rapid advances in medicine, effective pharmacological treatment against SCI has not yet been confirmed. This study aimed to investigate the possible anti-inflammatory, antiapoptotic, and neuroprotective effects of safinamide after SCI in a rat model.
View Article and Find Full Text PDFPurpose: Patients with polycystic ovarian morphology (PCOM) make up 20% cases for assisted reproductive technology (ART). Folliculogenesis is impaired in PCOS. Signaling molecules are involved in follicle development.
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