Publications by authors named "S Yesillik"
Article Synopsis
- Chronic spontaneous urticaria (CSU) negatively impacts patients' quality of life, and omalizumab is recommended for cases resistant to antihistamines; the Urticaria Activity Score-7 (UAS-7) measures disease severity.* -
- A study compared the long-term effectiveness and side effects of two doses (150 mg and 300 mg) of omalizumab in 108 CSU patients over 60 months, finding no significant differences in disease scores or adverse events between groups.* -
- The research concluded that starting with a 150 mg dose is adequate for CSU treatment, with an option to increase to 300 mg if needed, offering a potentially safer and more
Introduction: Anaphylaxis is a severe and life-threatening systemic hypersensitivity reaction. The most frequently encountered causes are foods, drugs, and bee venom, but anaphylaxis may also occur idiopathically. Paradoxical vocal cord movement (PVCM), is a cause of upper airway obstruction due to abnormal adduction of vocal cords during inspiration and, to some degree on expiration.
View Article and Find Full Text PDFBackground: Venom immunotherapy (VIT) is an effective treatment in the patients at high risk of anaphylaxis or life-threatening systemic reactions due to Hymenoptera venom allergy. But, systemic and large local reactions can be observed, especially during the build-up phase of VIT. We evaluated the safety of conventional and ultra-rush build-up protocols.
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- Nasal irrigation may help improve symptoms in children with intermittent allergic rhinitis (AR) when combined with nasal corticosteroids (NC), focusing on the effects of hyaluronic acid (HA) and normal saline solution (NSS).
- In a 28-day study involving 76 children, different groups received NC alone, NC plus NSS, or NC plus HA, with various nasal symptoms and quality of life measures taken before and after treatment.
- Results showed no major differences in symptom scores or quality of life among the groups, but the HA group did show a significant decrease in nasal airflow resistance, suggesting HA may have some benefits worth exploring further.
Background: Common variable immunodeficiency (CVID) is characterized by low immunoglobulin G and IgA/IgM, decreased switched memory B cells, impaired response to vaccine, and an increased susceptibility to infections and autoimmunity. T cells play an important role in germinal center reaction where it supports isotype switching, somatic hypermutation, generation of memory B cells, and differentiation of B cells to plasma cells. The objective was to study the distribution of three subsets of T cells and their relationship with autoimmune diseases associated with CVID.
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