Gated equilibrium radionuclide angiography (ERNA), or multigated acquisition scanning, is a well-established technique to monitor left ventricular ejection fraction (LVEF) in patients treated with potentially cardiotoxic chemotherapy. To determine the results of a true change in LVEF, low inter- and intrareader variability is important. The aim of this study was to investigate inter- and intrareader variability in LVEF measurements using 2 different commercially available software packages with cardiac MR (CMR) as a reference standard.
View Article and Find Full Text PDFNeurodegeneration in central nervous system disorders is linked to dysregulated neuronal calcium. Direct inhibition of glutamate-induced neuronal calcium influx, particularly via N-methyl-D-aspartate receptors (NMDAR), has led to adverse effects and clinical trial failures. A more feasible approach is to modulate NMDAR activity or calcium signaling indirectly.
View Article and Find Full Text PDFUnhealthy diets, including low fruit and vegetables (F&V) intake, contribute to morbidity and mortality related to non-communicable diseases. Designing culturally appropriate interventions to improve diets and F&V intake requires an in-depth understanding of individual-level dietary patterns, household consumption patterns, and nutritional status resulting from inadequate F&V intake. In this scoping review, we summarised the literature on diets, F&V intake, and nutritional status in Benin.
View Article and Find Full Text PDFSuboptimal diets contribute to the risk of malnutrition and non-communicable diseases across the life course. Globally, intakes of fruit and vegetables (F&V) fall below recommendations, including in the Philippines. To promote F&V intakes, understanding the extent of inadequate intakes across population groups and key drivers of dietary patterns is needed.
View Article and Find Full Text PDFGlobally, the intake of fruit and vegetables (F&V) is far below the recommended levels, contributing to various health challenges including micronutrient deficiencies and non-communicable diseases. In Tanzania, where the triple burden of malnutrition persists, there is a need to identify gaps in evidence, better understand diets and F&V intake and identify promising interventions for improved intake. We conducted a scoping review to summarize the evidence on dietary intake, F&V intake and nutritional status in Tanzania.
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