Disentangling Sources of Momentum Fluctuations in Xe+Xe and Pb+Pb Collisions with the ATLAS Detector.

High-energy nuclear collisions create a quark-gluon plasma, whose initial condition and subsequent expansion vary from event to event, impacting the distribution of the eventwise average transverse momentum [P([p_{T}])]. Disentangling the contributions from fluctuations in the nuclear overlap size (geometrical component) and other sources at a fixed size (intrinsic component) remains a challenge. This problem is addressed by measuring the mean, variance, and skewness of P([p_{T}]) in ^{208}Pb+^{208}Pb and ^{129}Xe+^{129}Xe collisions at sqrt[s_{NN}]=5.

Deciphering the evolving niche interactome of human hematopoietic stem cells from ontogeny to aging.

Hematopoietic stem cells (HSC) reside within specialized microenvironments that undergo dynamic changes throughout development and aging to support HSC function. However, the evolving cell-cell communication networks within these niches remain largely unexplored. This study integrates single-cell RNA sequencing datasets to systematically characterize the HSC niche interactome from ontogeny to aging.

Improved Kaempferol Solubility via Heptakis-O-(2-hydroxypropyl)-β-cyclodextrin Complexation: A Combined Spectroscopic and Theoretical Study.

Four cyclodextrins (CDs) including heptakis-O-(2-hydroxypropyl)-β-cyclodextrin (HP-β-CD), heptakis-O-(2,6-di-O-methyl)-β-cyclodextrin (DM-β-CD), β-cyclodextrin (β-CD), and γ-cyclodextrin (γ-CD) were evaluated for their ability to enhance the aqueous solubility of kaempferol (Kae). Phase solubility studies indicated that these four CDs can form 1:1 type complexes with Kae and that HP-β-CD demonstrated the most significant solubilizing effect on Kae. Among the CDs tested, HP-β-CD demonstrated the most significant solubilizing effect on Kae.

Precise diagnosis and prognosis assessment of malignant lung nodules: a narrative review.

Background And Objective: Pulmonary nodules (PNs) are small (≤3 cm) radiographic opacities within lung parenchyma. The use of low-dose computed tomography (LDCT) has led to a significant increase in the identification of solitary nodules. Malignant lung nodules comprise only 5% of all nodules, with management differing greatly from benign cases.

Ultrasound combined mechanical wall-breaking extraction of new Ganoderma leucocontextum polysaccharides and their application as a structural and functional improver in set fat-free goat yogurt production.

Herein, we investigate the yield, micro-structures, rheological properties and bioactivities of new Ganoderma leucocontextum polysaccharide (GLP) obtained from Kangding via ultrasound combined mechanical wall-breaking extraction (UBE), and examine the effect of GLP as a structural and functional improver on the physicochemical, sensory, aromatic, water-holding capacity (WHC), textural, rheological, micro-structural and protein structural properties, and bioactivities of set fat-free goat yogurt (set-FGY). Through response surface optimisation, the extracted GLP achieved a maximum yield of 2.18 %, showing good apparent viscosity and elastic behaviour in 3 % aqueous solution as well as good micro-structure and significant anti-oxidant and anti-diabetic activities.