Perceived discrimination as a predictor of cyberbullying: the mediating role of self-esteem and moderating role of self-compassion.

With the popularity of the internet, cyberbullying has emerged as an increasingly serious social issue, particularly affecting college students' behavioral health. This study explores the relationship between perceived discrimination and cyberbullying, as well as the mediating role of self-esteem and the moderating role of self-compassion (SC) in this relationship. Using a longitudinal design, data were collected from 892 Chinese college students (414 females, 478 males) in two waves spanning 1 year.

Methyl jasmonate induces the regulation of protostane triterpene biosynthesis by microRNAs in Alisma orientale.

Protostane triterpenes are medicinally important components found in members of the Alismataceae botanical family, notably Alisma orientale. Methyl jasmonate (MeJA) is known to regulate protostane triterpene biosynthesis in A. orientale, but the microRNA (miRNA) mechanism underlying MeJA response to promote triterpene biosynthesis remains unknown.

LMAN2 interacts with HEATR3 to expedite HER2-positive breast cancer advancement and inflammation and Akt/ERK/NF-κB signaling.

The paper aimed to reveal the impacts and the possible mechanism of action of lectin mannose-binding 2 protein (LMAN2) in HER2-positive breast cancer (BC). The expression, prognostic potential of LMAN2, and the correlation between LMAN2 and HEAT repeat containing 3 (HEATR3) in BC were analyzed in TCGA database. Intact, Mentha, and BioGrid databases predicted LMAN2-HEATR3 interactions.

Toxicity of Polystyrene Microplastics with Cadmium on the Digestive System of Tadpoles.

Microplastics pollution in freshwater systems is attracting increasing attention. However, our knowledge of its combined toxicity with heavy metals is scarce. In this study, was used as the model animal to study the combined poisoning mechanism of cadmium or microplastics on the digestive systems of tadpoles in freshwater.

The Emerging Scenario of Ferroptosis in Pancreatic Cancer Tumorigenesis and Treatment.

Pancreatic cancer remains one of the most lethal forms of cancer. Currently, there is a lack of effective drug treatments for pancreatic cancer. However, as a newly discovered form of non-apoptotic cell death, ferroptosis has garnered increasing attention in relation to pancreatic cancer.