Publications by authors named "S X Fan"

Introduction: This study protocol specifies the primary research line and theoretical framework of the 2023 Survey of the Psychology and Behavior of the Chinese Population. It aims to establish a consistent database of Chinese residents' psychological and behavioral surveys through multi-center and large-sample cross-sectional surveys to provide robust data support for developing research in related fields. It will track the public's physical and psychological health more comprehensively and systematically.

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Background/aim: Autosomal-recessive carnitine-acylcarnitine translocase deficiency (CACTD) is a rare disorder of long-chain fatty acid oxidation caused by variants in the SLC25A20 gene. Under fasting conditions, most newborns with severe CACTD experience sudden cardiac arrest and hypotonia, often leading to premature death due to rapid disease progression. Understanding of genetic factors and pathogenic mechanisms in CACTD is essential for its diagnosis, treatment, and prevention.

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The inhibition of the TIGIT/PVR interaction demonstrates considerable anticancer properties by enhancing the cytotoxic activity of natural killer (NK) and CD8+ T cells. However, the development of small molecule inhibitors that target TIGIT is currently limited. In this study, small molecules with the capacity to bind TIGIT and block the TIGIT/PVR interaction were screened through an advanced computational process, subsequently confirmed by blocking assays.

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A self-healing superhydrophobic coating was successfully prepared in the present work. The coating comprised PEG (polyethylene glycol) and FeO nanoparticles modified with stearic acid (SA) via hydrogen bonds, using polyamide resin and epoxy as binders. The chemically damaged surface could restore its original superhydrophobic structure and chemical composition after 4 h at room temperature or 10 min of heating in an oven with a self-healing efficiency of 95.

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Background: The psychological resilience of university students majoring in long-term-care (LTC)-related disciplines is crucial for workforce retention and effective care provision in this field. This study aims to investigate the differences in levels of psychological resilience among these students in Taiwan.

Methods: This cross-sectional study involved 258 participants selected via stratified random sampling from 23 universities across Taiwan from November 2021 to November 2022, representing a diverse educational context.

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