Publications by authors named "S Woodring"

Article Synopsis
  • A study was conducted to investigate whether low-dose naltrexone (LDN) can improve quality of life (QOL) and reduce fatigue in patients with high-grade glioma (HGG) during treatment.
  • 110 patients were randomly assigned to receive either LDN or a placebo for 16 weeks while undergoing radiation and temozolomide therapy.
  • Results showed that LDN did not significantly affect QOL or fatigue compared to the placebo, and both treatments had similar adverse effects attributed to the cancer therapy.
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Article Synopsis
  • Spirituality can significantly influence how patients with primary brain tumors approach treatment and end-of-life care, as evidenced by a strong connection between spiritual well-being (SWB) and health-related quality of life (HRQoL).
  • A study involving 606 patients revealed that those with higher spiritual well-being reported better quality of life, with various factors like belief in God, prayer, and personal circumstances also playing roles in this relationship.
  • The findings highlight the need to incorporate spiritual considerations into treatment strategies to enhance the overall quality of life for patients dealing with primary brain tumors.
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Background: Overall survival (OS) in glioblastoma (GBM) is poor at an average of 14 to 18 months, and long-term survivors (LTS) of GBM are rare. LTS of GBM, defined as surviving >5 years postdiagnosis, represent only 2% to 10% of all GBM patients. LTS of cancer are at high risk of developing second primary neoplasms.

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Purpose: CINV remains a distressing side effect experienced by glioma patients receiving multi-day temozolomide therapy, in spite of guideline-based antiemetic therapy with selective serotonin-receptor-antagonists. Antiemetic research with aprepitant has routinely excluded glioma patients. In this randomized open-label phase II study, use of a nonstandard 5-day regimen of aprepitant for glioma patients was investigated.

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Article Synopsis
  • Researchers investigated how many patients with primary brain tumors use complementary and integrative health interventions and their impact on quality of life.
  • A review of clinical records from late 2013 to early 2014 revealed that 76% of patients reported using these health practices, with vitamins, massage, and spiritual methods being the most common.
  • Despite the high usage rate, the study found no evidence that these practices improved patients' quality of life.
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