Respiratory syncytial virus infection in young hospitalized children. Identification of risk patients and prevention of nosocomial spread by rapid diagnosis.

Detection of RSV by immunofluorescence was used for rapid confirmation of the diagnosis in 89 infants during an epidemic. This made it possible to plan the care of the patients and use the personnel in an optimal way in order to maintain nosocomial infection at a low level. Somatic and environmental risk factors connected with serious disease were also identified.

Molecular epidemiology of adenoviruses: alternating appearance of two different genome types of adenovirus 7 during epidemic outbreaks in Europe from 1958 to 1980.

Four genome types of adenovirus serotype 7 (Ad7, Ad7a, Ad7b, and Ad7c) were identified by use of DNA restriction enzymes BamHI, EcoRI, and SmaI. We obtained information on the distribution of the four Ad7 genome types by typing 68 Ad7 isolates obtained in the Netherlands from 1958 to 1979 and 36 Ad7 isolates obtained in Sweden from 1964 to 1980. The Ad7 prototype was never detected, and only seven isolates were genome-typed Ad7a.

Correlation of herpes simplex virus types 1 and 2 with clinical features of infection.

Strains (338) of herpes simplex virus (HSV) were isolated in Stockholm during 1965-1974. By immunoelectroosmophoresis it was possible to identify all strains as either HSV type 1 (HSV-1) or 2 (HSV-2). No strains of intermediate antigenic type or with untypable characteristics were found.

Herpes simplex virus type 2 and acute aseptic meningitis. Clinical features of cases with isolation of herpes simplex virus from cerebrospinal fluids.

Herpes simplex virus (HSV) was recovered from the cerebrospinal fluids (CSF) of 10 patients with acute aseptic meningitis. HSV type 1 was isolated from the CSF of a 6-month-old boy. The other 9 HSV isolates from CSF were from adults in the age-group 15 to 29 years; 7 of these isolates were available for typing and were identified as HSV type 2.