Fine needle biopsy and scintigram in the preoperative diagnosis of thyroid lesions.

Fine needle biopsies (FNB) of the thyroid were examined from 860 patients. In 703 cases follicular cells without atypia were found and in this group of patients the clinical diagnosis was nodular goitre. Operations were performed in 138 patients and in 97 cases the cytological finding could be correlated to the histopathological diagnosis.

Histopathological systems of breast cancer classification: reproducibility and clinical significance.

The inter- and intraobserver reproducibilities of the histopathological systems of breast cancer classification suggested by the World Health Organisation (WHO), the Armed Forces Institute of Pathology (AFIP) and Ackerman have been analysed. The reproducibilities of the three classification systems were only "fair" to "moderate" and no correlation with the five-year recurrence rate was found. Our results indicate that these classification systems are without biological significance and are useless for prognosis in the individual patient.

Multifocal breast carcinoma.

The present study comprises 173 breast cancers in women living in Sweden. Mastectomy was performed and the surgical specimens were thoroughly scrutinized histopathologically with special attention given to the mammary tissue outside the dominant mass. Fifty-two patients (30 percent) had multifocal growth in the same breast as the dominant breast cancer.