A woman's attitude toward pregnancy. Can it predispose her to preterm labor?

A prospective study was designed to assess the relationship between a woman's attitude toward pregnancy, sociomedical factors and preterm labor among 434 consecutive pregnant women who filled out a self-reporting, multiple choice questionnaire at 24-28 weeks' gestation. The score on "poor investment in pregnancy," evaluating the maternal attitude toward pregnancy and the antepartum fetomaternal relationship, was the best predictor of preterm labor, followed by the risk score based upon sociomedical factors. Psychologic factors could play a significant role in the onset of preterm labor.

Itraconazole: a single-day oral treatment for acute vulvovaginal candidosis.

Itraconazole is an oral broad-spectrum antifungal agent with a propensity to leave the plasma and achieve high and persistent levels in tissues where fungi reside. Indeed, the highly lipophilic character of itraconazole results in a favourable tissue:blood ratio: most tissue concentrations exceed by far concentrations in the blood. Itraconazole has a depot effect in the skin and mucous membranes without leaking back into the plasma.

Veralipride versus conjugated oestrogens: a double-blind study in the management of menopausal hot flushes.

A double-blind, randomized study was carried out in 43 women, who had undergone spontaneous menopause at least 6 months earlier, to compare the effectiveness and tolerance of veralipride with that of a conjugated oestrogens preparation in the control of hot flushes. Twenty-one women received 100 mg veralipride per day and 22 were due to receive 1.25 mg per day of the hormone preparation over a period of 20 days but 3 women in the oestrogen group discontinued the trial without giving any reason.