Publications by authors named "S Watutantrige-Fernando"
We report the case of a 38-year-old man whose diagnostic workup for primary infertility led to the discovery of obstructive azoospermia due to bilateral papillary cystadenoma of the epididymis (PCE). Given the rarity of this finding and because PCE could be a manifestation of Von Hippel-Lindau disease (VHL), although the patient had no family or personal history of VHL, the gene was tested, and a known pathogenetic variant (c.464-1G>A; p.
View Article and Find Full Text PDFThis study aims to present the evolution of our center's approach to treating primary hyperparathyroidism (PHPT) from diagnosis to intraoperative interventions. We have also evaluated the intraoperative localization benefits of indocyanine green fluorescence angiography. This retrospective single-center study involved 296 patients who underwent parathyroidectomy for PHPT between January 2010 and December 2022.
View Article and Find Full Text PDFBackground: Thyroid hormone impairment, represented as an alteration in levels of thyroid hormones and a lower fT3/fT4 ratio, has been correlated with a worse prognosis for both cancer and non-cancer patients. The role of baseline thyroid function in patients with metastatic renal cell carcinoma (mRCC) however, has not been studied yet.
Materials And Methods: We recorded clinical data, baseline biochemical results, and oncological outcomes from 10 Oncology Units in Italy.
Article Synopsis
- A study evaluated clinical and molecular outcomes in differentiated thyroid carcinoma (DTC) across three groups: small tumors (≤ 40 mm), large tumors (> 40 mm), and those with distant metastases.
- Patients with metastatic DTC had the worst outcomes, experiencing higher rates of persistent disease, death, and need for further treatment, while outcomes were similar for non-metastatic groups regardless of size.
- Genetic analysis revealed distinct mutation patterns, with TERT promoter mutations indicating a worse prognosis, particularly in metastatic cases, and BRAF mutations being more common in smaller tumors.