Foraging and inertia: understanding the developmental dynamics of overt visual attention.

During early life, we develop the ability to choose what we focus on and what we ignore, allowing us to regulate perception and action in complex environments. But how does this change influence how we spontaneously allocate attention to real-world objects during free behaviour? Here, in this narrative review, we examine this question by considering the time dynamics of spontaneous overt visual attention, and how these develop through early life. Even in early childhood, visual attention shifts occur both periodically and aperiodically.

Finding order in chaos: influences of environmental complexity and predictability on development.

Environments are dynamic and complex. Some children experience more predictable early life environments than others. Here, we consider how moment-by-moment complexity and predictability in our early environments influence development.

Upstream targeting for the prevention of atrial fibrillation: Targeting Risk Interventions and Metformin for Atrial Fibrillation (TRIM-AF)-rationale and study design.

Background: Despite advances in ablation and other therapies for AF, progression of atrial fibrillation (AF) remains a significant clinical problem, associated with worse prognosis and worse treatment outcomes. Upstream therapies targeting inflammatory or antifibrotic mechanisms have been disappointing in preventing AF progression, but more recently genetic and genomic studies in AF suggest novel cellular and metabolic stress targets, supporting prior studies of lifestyle and risk factor modification (LRFM) for AF. However, while obesity is a significant risk factor, weight loss and risk factor modification have not been successfully applied in a US population with AF.

Needing to shout to be heard? Caregiver under-responsivity and disconnection between vocal signaling and autonomic arousal in infants from chaotic households.

Children raised in chaotic households show affect dysregulation during later childhood. To understand why, we took day-long home recordings using microphones and autonomic monitors from 74 12-month-old infant-caregiver dyads (40% male, 60% white, data collected between 2018 and 2021). Caregivers in low-Confusion Hubbub And Order Scale (chaos) households responded to negative affect infant vocalizations by changing their own arousal and vocalizing in response; but high-chaos caregivers did not, whereas infants in low-chaos households consistently produced clusters of negative vocalizations around peaks in their own arousal, high-chaos infants did not.