A Preliminary Analysis of a Prosocial Intervention to Support Teachers and Staff Implementing Behavioral Interventions in a Specialized School Setting.

Prosocial is a systems-level intervention framework that incorporates elements of acceptance and commitment therapy (ACT) with Ostrom's core design principles (CDPs) guiding effective organizations and collective action (Ostrom, 1990). We evaluated a Prosocial intervention to support teachers and staff in a specialized school. AB analysis supported improvements in group cohesion and values-behavior alignment during the intervention and pre-post analyses showed significant improvements in psychological flexibility and perceived stress of participants.

Blood Group B May Reduce Risk of Rebleeding in Patients With Upper Gastrointestinal Haemorrhage due to Peptic Ulcer Disease.

Risk stratification tools for the prediction of complications in patients with upper gastrointestinal haemorrhage are crucial for appropriate management. Blood group status has been associated with the risk of bleeding, thrombosis and risk of peptic ulcer disease (PUD). We assessed the influence of blood group status on rebleeding and other complications in 699 patients with PUD bleeding.

A Comprehensive Review of the Physical Examination for the Biceps-Labrum Complex of the Shoulder.

Biceps-labrum complex (BLC) disease is a well-established pain generator in the shoulder. Despite its ubiquity, BLC disease continues to pose a diagnostic challenge for orthopaedic surgeons. The use of magnetic resonance imaging and glenohumeral arthroscopy in the diagnosis of BLC disease has proven to be inadequate when performed independently.

Dual ASXL1 and CSF3R mutations drive myeloid biased stem cell expansion and enhance neutrophil differentiation.

Mutations in the epigenetic regulator Additional Sex Combs-Like 1 (ASXL1) are frequently observed in chronic neutrophilic leukemia (CNL). CNL is a myeloproliferative neoplasm (MPN) driven by activating mutations in the Colony Stimulating Factor 3 Receptor (CSF3R), which cause excessive neutrophil production. Despite the high rates of co-occurrence, the interplay between ASXL1 and CSF3R mutations in hematopoiesis and leukemia remains poorly understood.