Technology Use and Familiarity as an Indicator of Its Adoption in Museum by People with Intellectual Disabilities.

This paper describes the process of co-design of technological products to increase museum accessibility and engagement in visitors with mild or moderate intellectual disabilities (IDs). By using an Inclusive Research approach, a multidisciplinary team of experts, including researchers in Users Experience (UX), psychology, and education, museum curators and a group of participants with IDs (n=9) have participated as the research team. Participants with IDs were involved in two rounds of interviews.

Drug-eluting stent implantation in patients with acute coronary syndrome - the Activity of Platelets after Inhibition and Cardiovascular Events: Optical Coherence Tomography (APICE OCT) study.

Aims: To our knowledge, no randomised study has compared rates of uncovered stent struts in everolimus (EES) vs. new-generation zotarolimus-eluting (ZES-R) stents in acute coronary syndrome (ACS). The aim of our study was to evaluate the completeness of neointimal coverage with optical coherence tomography (OCT) in ACS patients treated with drug-eluting stents (DES) comparing EES versus new-generation ZES-R.

Synergy of molecular and serological methods in minimally invasive diagnosis of enteroviral cardiac infection.

Treatment of myocarditis and pericarditis can differ on the basis of aetiology: systemic or auto-immune disease can be positively influenced by corticoid therapy, whereas this kind of treatment can worsen the course of virus-induced disease. Therefore, the aetiological diagnosis is extremely important. The synergistic use of minimally invasive serological, IgG, IgM, IgA, and neutralizing titres, and RNA detection was evaluated on representative patients out of 238 suffering from cardiopathies.

The effect of alcohol on sexual risk-taking among young men and women.

The current study investigated the effects of alcohol and gender on the intentions of engaging in sexual risk-taking. Young adults (101 men, 99 women) were randomly assigned to the alcohol, placebo, or no-alcohol conditions. Participants listened to an audiotaped scenario that presented a romantic situation between a man and a woman who had just met.

Workflow comparison for label-free, quantitative secretome proteomics for cancer biomarker discovery: method evaluation, differential analysis, and verification in serum.

The cancer cell secretome has emerged as an attractive subproteome for discovery of candidate blood-based biomarkers. To choose the best performing workflow, we assessed the performance of three first-dimension separation strategies prior to nanoLC-MS/MS analysis: (1) 1D gel electrophoresis (1DGE), (2) peptide SCX chromatography, and (3) tC2 protein reversed phase chromatography. 1DGE using 4-12% gradient gels outperformed the SCX and tC2 methods with respect to number of identified proteins (1092 vs 979 and 580, respectively), reproducibility of protein identification (80% vs 70% and 72%, respectively, assessed in biological N = 3).