Publications by authors named "S W Shalaby"
Background: Portal vein system-specific risk factors contributing to portal vein thrombosis in cirrhosis are poorly investigated.
Aims: To quantify contact system and intrinsic pathway activation in peripheral compared to portal venous blood in patients with decompensated cirrhosis.
Methods: Adult patients with cirrhosis undergoing transjugular intrahepatic portosystemic shunt underwent simultaneous blood sampling from a peripheral vein and the portal vein.
Demographic factors, knowledge, attitude and perception and their association with nursing students' intention to use artificial intelligence (AI): a multicentre survey across 10 Arab countries.
BMC Med Educ
December 2024
Background: Artificial intelligence (AI) is becoming increasingly important in healthcare, with a significant impact on nursing practice. As future healthcare practitioners, nursing students must be prepared to incorporate AI technologies into their job. This study aimed to explore the associated factors with nursing students' intention to use AI.
View Article and Find Full Text PDFArticle Synopsis
- The study focused on identifying unique metabolomic signatures in patients with porto-sinusoidal vascular disorder (PSVD) and cirrhosis to improve diagnosis.
- Serum samples from healthy volunteers and patients with PSVD or cirrhosis were analyzed using advanced techniques like liquid chromatography-mass spectrometry, identifying significant metabolic changes linked to PSVD.
- Machine learning models were developed to distinguish PSVD from cirrhosis and healthy controls; key metabolites like taurocholic acid showed strong potential for non-invasive diagnostic use.
Portal vein thrombosis (PVT) is a frequent event among patients with advanced liver disease, with a prevalence reaching up to 26% in those awaiting liver transplantation (LT). Extensive thrombosis affecting the mesenteric vein confluence correlates with increased morbidity and mortality post-LT, particularly when it impedes physiological anastomosis or contraindicates the LT. Current guidelines advocate for routine PVT screening in all potential liver transplant candidates and prompt treatment upon detection.
View Article and Find Full Text PDFArticle Synopsis
- This study investigates the relationship between hepatic venous pressure gradient (HVPG) and direct portal pressure (DPP) in cirrhosis patients who still have esophageal varices (EV) after treatment to remove the underlying cause, even when HVPG is low (<10 mmHg).
- Ten patients with hepatitis C virus (HCV) or alcohol-related cirrhosis were examined, showing that HVPG correlates well with portal pressure measurements but doesn't fully explain the persistence of varices post-treatment.
- The research suggests that while HVPG reflects overall portal pressure accurately, the presence of varices after treatment needs further exploration, indicating a gap in understanding the benefits of treatment for patients with EV but low HVPG.