Publications by authors named "S W Mbugua"
Dementia prevention in Africa is critically underexplored, despite the continent's high prevalence of modifiable risk factors. With a predominantly young and middle-aged population, Africa presents a prime opportunity to implement evidence-based strategies that could significantly reduce future dementia cases and mitigate its economic impact. The multinational Africa-FINGERS program offers an innovative solution, pioneering culturally sensitive, multidomain interventions tailored to the unique challenges of the region.
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- This study explores the relationship between maternal genetics, human milk oligosaccharides (HMOs), and respiratory health in infants fed human milk.
- Researchers quantified 19 HMOs from 980 mothers and identified genetic markers linked to HMOs on several chromosomes, including notable findings on chromosomes 19 and 3.
- The study suggests that certain HMOs may help reduce the risk of respiratory issues, like recurrent wheezing, in preschoolers, depending on their genetic predispositions.
Article Synopsis
- The article discusses how traditional platinum-based cancer therapies may have limitations due to their reliance on classic homeostatic mechanisms for managing copper levels in the body.
- It highlights the significance of copper and its complexes, particularly copper dithiocarbamate, in enhancing cancer treatment effectiveness.
- The author suggests a shift in focus towards understanding and utilizing these copper mechanisms, potentially leading to new therapeutic strategies in cancer care.
At present, there is no internationally accepted set of core outcomes or measurement methods for epilepsy clinical practice. The International Consortium for Health Outcomes Measurement (ICHOM) convened an international working group of experts in epilepsy, people with epilepsy, and their representatives to develop minimum sets of standardized outcomes and outcome measurement methods for clinical practice. Using modified Delphi consensus methods with consecutive rounds of online voting over 12 months, a core set of outcomes and corresponding measurement tool packages to capture the outcomes were identified for infants, children, and adolescents with epilepsy.
View Article and Find Full Text PDFAt present, there is no internationally accepted set of core outcomes or measurement methods for epilepsy clinical practice. Therefore, the International Consortium for Health Outcomes Measurement (ICHOM) convened an international working group of experts in epilepsy, people with epilepsy and their representatives to develop minimum sets of standardized outcomes and outcomes measurement methods for clinical practice that support patient-clinician decision-making and quality improvement. Consensus methods identified 20 core outcomes.
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