F-18 FDG PET/CT based Preoperative Machine Learning Prediction Models for Evaluating Regional Lymph Node Metastasis Status of Patients with Colon Cancer.

Objective: This study aimed to develop a simple machine-learning model incorporating lymph node metastasis status with F-18 Fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) and clinical information for predicting regional lymph node metastasis in patients with colon cancer.

Methods: This retrospective study included 193 patients diagnosed with colon cancer between January 2014 and December 2017. All patients underwent F-18 FDG PET/CT and blood test before surgery.

Large-Scale Validation of the Feasibility of GPT-4 as a Proofreading Tool for Head CT Reports.

Background The increasing workload of radiologists can lead to burnout and errors in radiology reports. Large language models, such as OpenAI's GPT-4, hold promise as error revision tools for radiology. Purpose To test the feasibility of GPT-4 use by determining its error detection, reasoning, and revision performance on head CT reports with varying error types and to validate its clinical utility by comparison with human readers.

Solar-Driven High-Rate Ammonia Production from Wastewater Coupled with Plastic Waste Reforming.

Solar-powered electrochemical NH synthesis offers the benefits of sustainability and absence of CO emissions but suffers from a poor solar-to-ammonia yield rate (SAY) due to a low NH selectivity, large bias caused by the sluggish oxygen evolution reaction, and low photocurrent in the corresponding photovoltaics. Herein, a highly efficient photovoltaic-electrocatalytic system enabling high-rate solar-driven NH synthesis was developed. A high-performance Ru-doped Co nanotube catalyst was used to selectively promote the nitrite reduction reaction (NORR), exhibiting a faradaic efficiency of 99.

PrP Glycoprotein Is Indispensable for Maintenance of Skeletal Muscle Homeostasis During Aging.

Background: The cellular prion protein (PrP), a glycoprotein encoded by the PRNP gene, is known to modulate muscle mass and exercise capacity. However, the role of PrP in the maintenance and regeneration of skeletal muscle during ageing remains unclear.

Methods: This study investigated the change in PrP expression during muscle formation using C2C12 cells and evaluated muscle function in Prnp wild-type (WT) and knock-out (KO) mice at different ages (1, 9 and 15 months).

Soft coral Lobophytum crassum extract inhibits migration and induces apoptosis capabilities in human oral squamous cell carcinoma cells.

Background/purpose: The extract of the soft coral has shown an anti-cancer activity in various cancer cells. However, its effect on the oral squamous cell carcinoma cell (OSCC) lines remains unclear. The purpose of this study is to investigate the anti-cancer effects of the extract of (C127) on the OSCC cells.