Structures of Polyacetoxybriaranes Extracted from the Sea Whip Octocoral Junceella fragilis.

In the present study, an algae-containing octocoral, Junceella fragilis, was subjected to chemical screening. The analysis resulted in the extraction of six polyacetoxybriaranes: a new compound, identified as fragilide Z (1), alongside previously identified analogs, which included 12-epi-fragilide G (2), fragilide P (3), junceellolide D (4), junceellonoid A (5), and juncin ZI (6). The structures of compounds 2-6 were investigated through single-crystal X-ray diffraction analysis, whereas that of 1 was examined through two-dimensional nuclear magnetic resonance analysis.

Synthesis of polysubstituted tetrahydrofurans visible light-induced De Mayo acetalization of benzoylacetones.

A visible light photocatalytic cascade reaction was developed, involving sequential self-[2+2] photodimerization of benzoylacetones, De Mayo reaction, acetalization, and alkoxylation, yielding tetrahydrofurans with high stereoselectivity, three stereogenic centers, and two quaternary carbons, under mild conditions with a cycloaddition-rearrangement strategy. Given the significance of photoreaction and rearrangement in organic chemistry, this method provides a valuable approach for the synthesis of tetrahydrofurans.

Swing limb detection using a convolutional neural network and a sequential hypothesis test based on foot pressure data during gait initialization in individuals with Parkinson's disease.

. Start hesitation is a key issue for individuals with Parkinson's disease (PD) during gait initiation. Visual cues have proven effective in enhancing gait initiation.

Supramolecular Assembly, Solvent-Induced, and Mechanochromic Luminescence of Au(I) Quinoline-8-thiolates.

AuCl(PMe) and AuCl(PEt) were used to react with quinoline-8-thiolate (8-QNS) to give three Au(I) complexes, i.e., [8-QNS(AuPMe)]ClO (), [(8-QNS)Ag(AuPMe)]ClO (), and [8-QNS(AuPEt)]ClO (), which have been structurally determined by X-ray diffraction to show various intra- and intermolecular metal···metal contacts (i.