Indian J Psychol Med
July 2014
A 57 years old married, retired official of Indian Railway service presented with two months complaints of recurrent fears of circulation of a duplicate CD of one of his presentations in an international conference, recurrent thoughts that the years of winning medals during his tenure in Indian Railways service were misrepresented in the records as early years. He recognized these fears as irrational, intrusive causing irritability and extreme anxiety, as he felt an urge to go and check the records, and feared it would cause humiliation. A diagnosis of obsessive compulsive disorder predominantly obsessions were made.
View Article and Find Full Text PDFStudy Question: Can amino acid profiling differentiate between human oocytes with differing competence to mature to metaphase II (MII) in vitro?
Summary Answer: Oocytes which remained arrested at the germinal vesicle (GV) stage after 24 h of in vitro maturation (IVM) displayed differences in the depletion/appearance of amino acids compared with oocytes which progressed to MII and patient age, infertile diagnosis and ovarian stimulation regime significantly affected oocyte amino acid turnover during IVM.
What Is Known Already: Amino acid profiling has been proposed as a technique which can distinguish between human pronucleate zygotes and cleavage stage embryos with the potential to develop to the blastocyst stage and implant to produce a pregnancy and those that arrest. Most recently, the amino acid turnover by individual bovine oocytes has been shown to be predictive of oocyte developmental competence as indicated by the gamete's capacity to undergo fertilization and early cleavage divisions in vitro.
Patients with anovulatory infertility, who received treatment at one unit over a four year period, were assessed to determine the pregnancy rate and the incidence of complications while undergoing ovulation induction with gonadotropins. The patients in this group who had further in vitro fertilization (IVF) treatment were followed up, and the outcome in IVF cycles was assessed. Data from a total of 75 patients, who had completed 91 episodes of treatment involving 273 cycles of ovulation induction over a 4-year period in a University-affiliated teaching hospital, was analysed retrospectively.
View Article and Find Full Text PDFThe aim of this retrospective study was to assess the pregnancy outcome and incidence of severe ovarian hyperstimulation syndrome (OHSS) in patients at risk of developing OHSS who had embryo cryopreservation at pronucleate stage and deferred embryo transfer in a university-affiliated teaching hospital over a 5-year period. Elective embryo cryopreservation and deferred transfer in patients at risk of OHSS does not compromise the cumulative pregnancy rate per patient and also results in a low overall incidence of severe OHSS.
View Article and Find Full Text PDFHum Fertil (Camb)
December 2004
We conducted a postal survey to find out the current practice in the UK regarding the methods employed to assess tubal patency. A questionnaire was developed to evaluate the methods used to assess tubal patency in women presenting with infertility with or without risk factors suggesting pelvic disease. A total of 496 questionnaires were sent and 174 responded (35%).
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