Tuberculosis, granulomatosis with polyangiitis, or both? A case report.

Introduction: Tuberculosis (TB) is a chronic granulomatose infection, and granulomatosis with polyangiitis (GP) is a small vessel vasculitis, both of which affect the lungs. The combination of these diseases is rare. Both have similar clinical features, making the differential diagnosis difficult.

Pars planitis is associated with an increased frequency of effector-memory CD57+ T cells.

Aim: To evaluate the frequency, phenotype and the potential function of CD57+ T cell subsets in patients with pars planitis.

Methods: CD4+CD57+ and CD8+CD57+ T cells were quantitated in peripheral blood from 15 patients with pars planitis and 15 healthy controls. To evaluate the phenotype and potential function of CD57+ T cell subsets CCR7, CD27, CD28, CD45RA, CD45RO, intracellular IFN-gamma, IL-4, perforin and granzyme-A expression were assessed by flow cytometry.

[Diagnosis of Wegener's granulomatosis in patients with ocular inflamatory disease].

Objective: Report the ophthalmologic manifestations among patients with Wegener 's Granulomatosis (WG).

Method: We reviewed the database of the Instituto de Oftalmologia Fundación Conde de Valenciana in order to collect information regarding complete ophthalmic examination, laboratory and cabinet tests, treatment, and disease progression.

Results: We included 11 patients with WG (18 eyes).