Publications by authors named "S Vinnicombe"
Background: Children and young people with experience of being in care (e.g. foster care, kinship care, residential care or at home with a supervision requirement order) are at higher risk of adverse mental health and well-being outcomes compared to the general population.
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- Elevated mammographic density (MD) is a significant risk factor for breast cancer, and this study investigates how factors like childbirth, age at first birth, and breastfeeding relate to MD in a large group of women across different countries.
- The research analyzed data from 11,755 women aged 35-85 years, focusing on how factors such as the number of births and the timing of the first birth influence measurements of MD.
- The findings suggest that having more children decreases MD, while older age at first birth is linked to higher MD, particularly in post-menopausal women, highlighting the complex relationships between reproductive factors and breast density.
BACKGROUND Hereditary breast cancer arising in BRCA1-deficient patients is commonly diagnosed as invasive carcinoma of no special type (NST) with medullary features, while invasive lobular carcinoma (ILC) appears to be significantly under-represented in BRCA1 mutation carriers. We report a case of pleomorphic ILC arising in a 28-year-old woman harboring a germline BRCA1 c.3756_3759delGTCT p.
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- Abbreviated breast MRI, called FAST MRI, helps doctors screen women with dense breasts or those who have a history of breast cancer.
- A special training program was made for doctors to improve their skills in reading FAST MRI scans by giving them immediate feedback on their results.
- After training, 43 doctors tested their ability to read scans and showed good results, with a high agreement on identifying true outcomes, especially when they read more scans.