Alteration in bone marrow RNA of vitamin E-deficient monkey, Macaca fascicularis.

In anemic crab-eating monkeys, Macaca fascicularis, there is an alteration in the bone marrow RNA species resulting from early vitamin E deficiency, when compared with those from normal simian bone marrow or from phenylhydrazine-induced anemic bone marrow of rabbit. Anemia of vitamin E deficiency is specifically associated with a reduction in the ribosomal RNA content.

Resolution of the initial phase controversy in the thiamine-polyphenol reaction.

The kinetics of interactions between thiamine and seven polyphenols were followed by two types of thiochrome assays. The assays on the reaction mixture showed the extremely rapid initial phase whereas those on the eluate of the mixture previously treated by the Decalso column did not. The former assay methods also produced higher estimates of thiamine modification than the latter over the period of 3 hours of reaction.

Chemical interactions between thiamin and tannic acid. I. Kinetics, oxygen dependence and inhibition by ascorbic acid.

Consumption of food high in tannins can cause thiamin deficiency. The interactions between tannic acid and thiamin were studied by allowing them to react at pH 7.5, 60 C, and determining free remaining thiamin by the thiochrome method and by recording changes in ultraviolet absorption profiles at intervals.