Publications by authors named "S Vijayaprakash"
Influence of limonin on Wnt signalling molecule in HepG2 cell lines.
J Nat Sci Biol Med
January 2013
Article Synopsis
- Limonin has shown potential as a powerful anti-cancer agent, particularly against human liver cancer cells (HepG2), as demonstrated through cell viability and LDH leakage assays.
- The study provided evidence of limonin inducing apoptosis in HepG2 cells, confirmed by western blot analysis focusing on key proteins like Bax and Caspases.
- Limonin was found to downregulate Wnt signaling pathway components (LRP5, LRP6, and DKK), suggesting its effectiveness warrants further research in cancer treatment.