Publications by authors named "S Verfaillie"
Article Synopsis
- Topotecan is the standard treatment for relapsed small-cell lung cancer (SCLC), with both oral and intravenous forms being equally effective, but oral treatment has fewer side effects.
- A case study presented a patient with stable disease after using oral topotecan; however, when switched to intravenous topotecan due to supply issues, the patient experienced significant disease regression after one dose.
- This report highlights the first known instance of intravenous topotecan showing a better response than oral topotecan, with no clear reasons found for this difference.
Immune checkpoint inhibitors (ICIs) targeting PD-(L)1 and CTLA-4 have revolutionized the systemic treatment of non-small cell lung cancer (NSCLC), achieving impressive results. However, long-term clinical benefits are only seen in a minority of patients. Extensive research is being conducted on novel potential immune checkpoints and the mechanisms underlying ICI resistance.
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- Lateral cord plantar fasciitis (LCPF) is a foot condition that causes pain near the pinky toe and was treated in this study.
- Researchers used PRP injections and a walking cast to help patients, checking their pain levels at different times after treatment.
- The results showed that pain decreased significantly after treatment and patients continued to feel better up to two years later.
It is unclear how self-reported severe fatigue and difficulty concentrating after SARS-CoV-2 infection relate to objective neuropsychological functioning. The study aimed to compare neuropsychological functioning between individuals with and without these persistent subjective complaints. : Individuals with and without persistent severe fatigue (Checklist Individual Strength (CIS) fatigue ≥ 35) and difficulty concentrating (CIS concentration ≥ 18) at least 3 months after SARS-CoV-2 infection were included.
View Article and Find Full Text PDFBackground: To address the growing prevalence of youth mental health problems, early intervention is crucial to minimize individual, societal, and economic impacts. Indicative prevention aims to target emerging mental health complaints before the onset of a full-blown disorder. When intervening at this early stage, individuals are more responsive to treatment, resulting in cost-effective outcomes.
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