Publications by authors named "S Vatovec"
Bacillus subtilis is a widespread and diverse bacterium t exhibits a remarkable intraspecific diversity of the ComQXPA quorum-sensing (QS) system. This manifests in the existence of distinct communication groups (pherotypes) that can efficiently communicate within a group, but not between groups. Similar QS diversity was also found in other bacterial species, and its ecological and evolutionary meaning is still being explored.
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- ALS and FTLD are severe neurodegenerative diseases linked by dysfunctional RNA metabolism, characterized by the aggregation of RNA binding proteins.
- The discovery of a hexanucleotide repeat expansion (GGGGCC) in the C9ORF72 gene is the most common genetic cause of both conditions and contributes to the pathology by disrupting RNA processes and forming toxic structures.
- Understanding the mechanisms behind these diseases, including the role of key proteins like TDP-43, is crucial for developing potential treatments.
Many angiosperms use specific interactions between pollen and pistil proteins as "self" recognition and/or rejection mechanisms to prevent self-fertilization. Self-incompatibility (SI) is encoded by a multiallelic S locus, comprising pollen and pistil S-determinants. In Papaver rhoeas, cognate pistil and pollen S-determinants, PrpS, a pollen-expressed transmembrane protein, and PrsS, a pistil-expressed secreted protein, interact to trigger a Ca(2+)-dependent signaling network, resulting in inhibition of pollen tube growth, cytoskeletal alterations, and programmed cell death (PCD) in incompatible pollen.
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