Publications by authors named "S Vasugi"

Cancer remains a major global health concern due to several factors. These include the difficulty in accessing effective drugs, the high toxicity of available treatments, and the emergence of resistance to therapy. As a result, alternative strategies, such as the use of microbial enzymes, have gained attention as potential solutions to these challenges.

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Introduction  Cancer remains a significant health challenge, and nanoparticles (NPs) are promising candidates for cancer treatment due to their unique physicochemical properties and ability to selectively target tumour cells. Two-dimensional (2D) nanomaterials, such as MXenes, have attracted interest due to their electronic structures, optical properties, catalytic abilities, and exceptional physicochemical attributes. MXenes are highly suitable for surface functionalization or modification, and their unique properties make them promising candidates for various applications in the biological field.

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Background The two-dimensional MXene, known as titanium carbide (Ti₃C₂), is characterized by its substantial interlayer spacing, extensive surface area, hydrophilic nature, exceptional thermal stability, and outstanding electrical conductivity. These distinctive attributes render Ti₃C₂ an ideal candidate for detecting target analytes and immobilizing biomolecules. Bismuth oxide (Bi₂O₃), an essential compound of bismuth, frequently acts as a foundational element in bismuth chemistry.

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Article Synopsis
  • Rubella, caused by a single-stranded RNA virus, can be effectively prevented through vaccination, and molecular docking is used to explore potential drug interactions with the virus's proteins.
  • This study focused on a marine-derived compound, Rhizophorin, to assess its antiviral properties against the rubella capsid virus by using advanced docking techniques.
  • Results indicated that Rhizophorin exhibits strong binding affinity to the rubella capsid protein, with critical hydrogen and hydrophobic interactions that highlight its potential as a therapeutic agent.
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Introduction  MXenes (TiC) represent a group of two-dimensional inorganic compounds, produced through a top-down exfoliation method. They comprise ultra-thin layers of transition metal carbides, or carbonitrides, and exhibit hydrophilic properties on their surfaces. Utilizing TiC BiOCl nanoparticles for their antimicrobial and antioxidant attributes involves enhancing synthesis, processing, and characterization techniques.

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