Introduction Acute cholecystitis, commonly caused by gallstones, is a prevalent surgical emergency worldwide. Laparoscopic cholecystectomy (LC) is the gold standard for treatment, but the timing is crucial, with early surgery (within seven days) reducing complications. Identifying prognostic factors such as age, sex, white blood cell (WBC) count, C-reactive protein (CRP), and gallbladder wall thickness can help predict outcomes and reduce the need for conversion to open surgery.
View Article and Find Full Text PDFEnormous amounts of toxic synthetic dyes and inorganic contaminants, such as heavy metals, are regularly discharged into local water bodies unregulated and untreated through effluents from a wide range of industries. Designing industrial methodologies that limit or eliminate the unloading of harmful substances in the surrounding environment has become a requisite for sustainable growth. Although the magnetic separation-based adsorption technique seems quite promising, the functional moieties on the nanoparticle surface often restrict the choice of target pollutants, limiting their universal applicability.
View Article and Find Full Text PDFDengue virus (DENV), a common and prevalent mosquito-borne endemic disease, is caused by four serotypes (DENV-1-4) and has spread rapidly on a global scale over the past decade. A crucial step in the development of antiviral therapeutics requires the utilization of in vitro cell-based techniques, such as plaque assays and focus-forming assays (FFA) for virus quantification. Vero cells have been widely used for FFA and plaque assay; however, there are instances when their efficacy and efficiency in the detection of certain clinical DENV isolates are low.
View Article and Find Full Text PDFBackground & Aim: Polycystic Ovary Syndrome (PCOS) is a complex endocrine disorder that affects women throughout their reproductive age and characterised via polycystic ovaries, hyperandrogenism, and irregular menstruation. There is rising evidence that the pathophysiology of PCOS is significantly affected via the gut microbiota and its metabolic products.
Methods: This narrative review synthesizes current literature exploring the relationship between gut microbiota and PCOS.