Publications by authors named "S Vardasbi"

Article Synopsis
  • The study investigated the impact of chicory seed extract (CI) on liver fat accumulation (steatosis) in diabetic rats and liver cells (HepG2) using two different experimental setups.
  • CI showed promising results by preventing significant liver damage (steatosis-inflammation-fibrosis) when applied simultaneously with the fat-inducing compound, while in non-simultaneous treatment, it improved gene expression linked to fat metabolism.
  • CI was found to contain components like caffeic acid and chlorogenic acid and acted as a PPARα agonist, indicating its potential role in addressing different phases of hepatic steatosis.
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Background And The Purpose Of The Study: Melatonin has recently been found in several plant tissues. Some reports show that the majority of the herbs containing the high level of melatonin have been used traditionally to treat neurological disorders or diseases associated with the generation of free radicals. Current study was undertaken to screen some medicinal plant species with historical evidence of efficacy in the treatment of neurological and antioxidant deficiency related disorders for their melatonin content.

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Background: Osteogenesis driven by adipose-derived stem cells (ADSCs) is regulated by physiological and pathological factors. Accumulating evidence from in vitro and in vivo experiments suggests that melatonin may have an influence on bone formation. However, little is known about the effects of melatonin on osteogenesis, which thus remains to be elucidated.

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The blood glucose lowering effect of Urtica dioica (Stinging Nettle) as a medicinal plant has been noted in old writings such as those of Avicenna. Recently, there has also been other investigators that indicated the hypoglycemic effect of Urtica dioica. But so far, the mechanism of this effect has not been deduced.

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