Self-Assembly of Hausmannite MnO Triangular Structures on Cocosin Protein Scaffolds for High Energy Density Symmetric Supercapacitor Application.

Recent advances in using biological scaffolds for nanoparticle synthesis have proven to be useful for preparing various nanostructures with uniform shape and size. Proteins are significant scaffolds for generating various nanostructures partly because of the presence of many functional groups to recognize different chemistries. In this endeavor, cocosin protein, an 11S allergen, is prepared from coconut fruit and employed as a potential scaffold for synthesizing MnO materials.

Isolation and characterization of an iridoid, Arbortristoside-C from - Linn., a potential drug candidate for diabetes targeting α-glucosidase.

Many parts of the plant Linn. are widely investigated for their biological properties. Purified Arbortristosides from seeds are reported as anticancer, anti-leishmania, anti-inflammatory, anti-allergic, immunomodulatory and antiviral.

Structure-based drug designing towards the identification of potential anti-viral for COVID-19 by targeting endoribonuclease NSP15.

The world is facing health and economic havoc due to the Corona Virus Disease-2019 (COVID-19) pandemic. Given the number of affected people and the mortality rate, the virus is undoubtedly a serious threat to humanity. By analogy with earlier reports about Severe Acute Respiratory Syndrome (SARS-CoV) and Middle East Respiratory Syndrome (MERS-CoV) - viruses, the novel Coronavirus' replication mechanism is likely well understood.

Crystallographic and calorimetric analysis on Pleurotus ostreatus lectin and its sugar complexes - promiscuous binding driven by geometry.

Carbohydrate recognition is established as a property of lectins and implicated in many functions including immunity and defense against pathogens. Many lectins are characterized and proposed for various applications owing to the above said recognition. The crystal structure of a lectin from Pleurotus ostreatus has been determined and shown to be calcium dependent.

Crystal structure of a novel Kunitz type inhibitor, alocasin with anti-Aedes aegypti activity targeting midgut proteases.

Background: The pesticidal properties of many Kunitz-type inhibitors have been reported previously; however, the mechanism of action is not well established. In this study, the activity of alocasin against Aedes aegypti is demonstrated and the structure-activity relationship of this Kunitz-type inhibitor is explained through X-ray structure analyses.

Results: Alocasin was purified from mature rhizomes of Alocasia as a single polypeptide chain of ∼ 20 kDa.