[Uveitis, caused by Echo-11 virus].

Analysis of clinical manifestations of a total enteroviral infection with ECHO-11 virus-induced uveitis in 58 infants aged 2 weeks to 1.5 years has shown that uveitis develops on days 1-10 of the disease and is associated with a weak injection, endothelial edema, hyperemia and edema of the iris rapidly eventuating in destruction of the pigment lamina and fenestration. Posterior synechiae, pupil deformations, grave uveitis with hypotonia of 4-10 mm Hg are rapidly developing.

[The geographical spread of enterovirus uveitis in the USSR].

Enteroviral uveitis is accompanied by intensive and long-term production of specific neutralizing antibodies. The antibody titer to the causative virus ECHO 19/K (Siberia, Krasnoyarsk, 1980-1981) was 1:1000-1:65,000 in 80% of children 5 to 6 1/2 years after the illness. In retrospective examinations of blood sera from children with the history of uveitis using a neutralization test with ophthalmotropic strains of ECHO 19 and ECHO 11 viruses, the ECHO-virus etiology of this disease was first established in 80 patients living in the European part of the country (Moscow, Leningrad, Volgograd, Krasnodar, Donetsk, etc) and in the Caucasus (Yerevan, Tbilisi, Baku).

[Outbreak of enteroviral uveitis in children in Omsk in 1987-1988].

From May, 1987, to July, 1988, 56 cases of acute enterovirus infection complicated by uveitis were reported in Omsk, Western Siberia, USSR. Infants aged from 15 days to 19 months were involved. The infection was nosocomial, the peak of the incidence occurring in January 1988.