[Forced insulin coma therapy and its efficacy].

The title method was applied to the treatment of schizophrenic patients suffering from schizoaffective, paranoid and hallucinatory paranoid attacks. Definite correlations were established between the development of insulin coma and the type of the reverse development of psychosis. Five variants of schizophrenia reduction due to the treatment method under consideration were distinguished and described: variant 1--harmonic critical, variant 2--harmonic lytic, variant 3--disharmonious deliric, variant 4--disharmonious affective, and variant 5--incomplete reduction.

[Effect of prior psychopharmacotherapy on the development, clinical course and therapeutic effect of insulin coma in patients with schizophrenia].

In 123 patients the peculiarities of formation and effectiveness of insulin coma (IC) were studied under drug therapy as compared with 49 drug-free patients. Pharmacotherapy preceding the ICs produced uneven effect on its course. Artefact course of IC was most frequently observed after mageptil, chlorpromazine melipramine treatment, and to a lesser extent--after haloperidol, triphtazin, amitriptyline.