Publications by authors named "S V Sowmya"
Pathological Sequelae of Chronic Vestibular Migraine and Cerebrovascular Insufficiency Leading to Cognitive Decline and Dementia.
Indian J Otolaryngol Head Neck Surg
February 2025
Chronic vestibular migraine (CVM) and cerebrovascular insufficiency are recognized contributors to cognitive impairment. Vestibular dysfunction affects spatial orientation and balance, while compromised cerebral perfusion impacts neuronal health. This study explores the combined pathological effects of these conditions and their role in cognitive decline and dementia.
View Article and Find Full Text PDFGingival Mesenchymal Stem Cells: A Periodontal Regenerative Substitute.
Tissue Eng Regen Med
January 2025
Background: Gingival mesenchymal stem cells (GMSCs) are distinctive homogenous subset of mesenchymal stem cells (MSCs), which has its development from neural ectomesenchyme along with contributions from the perifollicular mesenchyme and the dental follicle proper. GMSCs stand apart from other dental MSCs owing to their ease of accessibility and availability with incredible long culture sustainability without any tumorigenic capability, and stable telomerase activity. Their capacity to differentiate into various cell lineages and inherent therapeutic effect in chronic inflammatory diseases like colitis, rheumatoid arthritis, systemic lupus erythematous (SLE) and diabetes makes them immensely valuable.
View Article and Find Full Text PDFArticle Synopsis
- Oral lichen planus (OLP) is a chronic inflammatory condition affecting the oral mucosa, which can severely impact patients' quality of life due to discomfort and anxiety.
- A study at Saveetha Dental College analyzed the anxiety and depression levels of 212 OLP patients, with their data collected over one year, including factors like age, gender, and associated medical conditions.
- The study found that the most affected age group was 51-60 years, predominantly female, with many reporting burning sensations as the main symptom, and a small percentage having comorbidities like Grinspan syndrome.
Background: By resolving the difficulties associated with missing teeth, implant-supported restorations have emerged as a key component of contemporary dentistry. The choice of prosthetic materials is crucial in establishing the durability and clinical efficacy of these restorations.
Methods: A prospective design was used at a tertiary care hospital with 150 patients receiving implant-supported restorations.
Article Synopsis
- Epilepsy affects around 50 million people globally, leading to challenges in motor skills that subsequently impact oral health, especially in developing countries.
- A study conducted at Saveetha Dental College, Chennai, compared oral health issues between 105 South Indian adults with epilepsy and 105 healthy controls, revealing that epileptic patients had significantly poorer oral health outcomes.
- The results indicated higher prevalence of gingival hyperplasia and a greater need for dental procedures in epileptic individuals, signaling an urgent need for improved dental care for this population.