Negligible Long-Term Impact of Nonlinear Growth Dynamics on Heterogeneity in Models of Cancer Cell Populations.

Linear compartmental models are often employed to capture the change in cell type composition of cancer cell populations. Yet, these populations usually grow in a nonlinear fashion. This begs the question of how linear compartmental models can successfully describe the dynamics of cell types.

Wheelchair users function and satisfaction with modified wheelchair and intermediate wheelchair services in Pakistan.

Wheelchair users with poor trunk control and postural abnormalities require additional posture support devices and wheelchair modifications to sit upright. Therefore, this study was conducted to observe the function of wheelchair users in the modified wheelchair and their satisfaction with both the modified wheelchair and intermediate wheelchair service. A descriptive study was conducted, and 14 participants were recruited through consecutive sampling.

Basic Science and Pathogenesis.

Background: Alzheimer's disease (AD) has traditionally been recognized as progressive dementia with brain deposits of amyloid (Aβ) and Tau (MAPT) proteins starting 20 and 10 years before the onset of clinical symptoms. Aggregation and deposition of Aβ and Tau proteins have been successfully studied in vitro, cell cultures, and animal models, but clinical deficits have been more difficult to assess. Behavior in mice is a complex phenomenon and subject to variation based on mouse interest, moods, stress-induced distraction, and other undefined parameters.

Comparative evaluation of pattern and distribution of stresses in single- and double-implant overdenture using ball-ring, positioner, and magnet-keeper attachment under different loading conditions: A finite element analysis.

Aim: The aim is to evaluate and compare stress distribution characteristics of ball, magnet, and positioned attachment systems in single and double implant-retained overdentures using the finite element method (FEM).

Setting And Design: In vitro (in silico study) finite element analysis (FEA).

Materials And Methods: A Styrofoam mandible with duplicated silicon mucosa was used to construct a mandibular complete denture.

"Joint protection first": understanding physiotherapists' implementation of evidence-based interventions in osteoarthritis knee management-a qualitative study.

Purpose: To explore the factors that influence physiotherapists' adherence to evidence-recommended interventions in the management of knee osteoarthritis.

Materials And Methods: Using a qualitative descriptive design, we conducted semi-structured interviews with 15 physiotherapists across India. Participants were selected using purposive sampling to ensure diversity in experience and setting.