Publications by authors named "S V Samoilova"

Article Synopsis
  • Cervical cancer is a significant health issue among young women, prompting the need for better diagnosis and treatment methods, particularly focusing on photodynamic therapy (PDT) using chlorin e6 (Ce6).
  • A clinical study with 94 women evaluated the effectiveness of PDT versus traditional conization treatments, finding that those who received PDT showed greater improvement in cytological outcomes and fewer cervical lesions.
  • Results indicated that patients undergoing PDT had better reproductive outcomes, demonstrating its higher clinical efficacy and safety in treating cervical preinvasive conditions compared to standard surgical treatment.
View Article and Find Full Text PDF

(1) Purpose: To investigate the efficacy and safety of using PDT in the treatment of severe intraepithelial squamous lesions of the cervix and preinvasive cervical cancer associated with HPV in women of reproductive age. (2) Methods: The examination and treatment of 45 patients aged 22-49 years with morphologically confirmed HPV-associated cervical intraepithelial neoplasia of a severe degree (17 patients) and preinvasive cervical cancer (28 patients) were performed. All patients underwent PDT of the cervix using a chlorin e6 photosensitizer; after which, the affected areas of the cervix were evaluated using video and spectral fluorescence diagnostics.

View Article and Find Full Text PDF

In male rats, acute renal failure was simulated by clamping the vascular pedicle of the left kidney for 60 or 90 min and right-sided nephrectomy. In the control series, no therapy was performed. In the experimental series, the animals were daily injected subcutaneously with Cellex, a protein-peptide complex (PPC) chromatographically isolated from the brain tissue of pig embryos with a molecular weight of its components from 10 to 250 kDa.

View Article and Find Full Text PDF

This paper presents a method to retrieve the particle size distribution function from the data of vertical lidar sensing. We have used 462 data models obtained at the Zvenigorod AERONET site obtained in 2011-2012. For each laser shot, we considered both fine (with particle sizes in a range from 0.

View Article and Find Full Text PDF

The paper reviews the 2016 WHO classification of prostate tumors, notes the alterations made, and describes approaches to the diagnosis of cancer types and grades. It also gives original photomicrographs from the authors' collection. The main alterations were as follows: - The types of prostate adenocarcinoma were added by pleomorphic giant-cell carcinoma; oncocytic (8290/3) and lymphoepithelial (8082/3) carcinomas were excluded.

View Article and Find Full Text PDF