Publications by authors named "S V Ramanan"
Connected speech samples elicited by a picture description task are widely used in the assessment of aphasias, but it is not clear what their interpretation should focus on. Although such samples are easy to collect, analyses of them tend to be time-consuming, inconsistently conducted and impractical for non-specialist settings. Here, we analysed connected speech samples from patients with the three variants of primary progressive aphasia (semantic, svPPA = 9; logopenic, lvPPA = 9; and non-fluent, nfvPPA = 9), progressive supranuclear palsy (PSP Richardson's syndrome = 10), corticobasal syndrome (CBS = 13) and age-matched healthy controls ( = 24).
View Article and Find Full Text PDFDuchenne muscular dystrophy (DMD) is a severe genetic disorder characterized by progressive muscle degeneration, primarily affecting young males. In this study, we investigated arginine-modified hydroxyapatite nanoparticles (R-HAp) as a novel non-viral vector for DMD gene therapy, particularly for delivering the large 18.8 kb dystrophin gene.
View Article and Find Full Text PDFArticle Synopsis
- Degraded semantic memory is a key feature of frontotemporal dementia (FTD), affecting both social and general knowledge, particularly in cases of semantic dementia and anterior temporal lobe (ATL) atrophy.
- Recent research has focused on how social-semantic knowledge is impacted in FTD, with a specific interest in the role of the right ATL compared to the left ATL.
- A study involving various FTD types and control groups found that social and non-social semantic deficits were significantly correlated in FTD, while unilateral ATL resection led to milder impairments without clear left/right differences in knowledge.
Introduction: Permanent pacemaker implantation (PPI) in neonates is challenging with respect to indications, device selection, implantation technique, and long-term outcomes. Complex anatomy, the need for long-term pacing with high rates, and a problematic postoperative period are the major problems.
Methods: We prospectively followed up 22 newborns who underwent PPI below 28 days of life at our institute.