[Databases as instruments for analysis of large-scale data sets on interactions between molecular biological objects].

We have surveyed the most well-known and accessible informational resources, consolidating data on interactions of molecular biological objects. Three main criteria are discussed: quality (coverage and reliability) of the information present, ability to analyze experimental data, and ease of results visualization. Several algorithms of data analysis, base on various types of resources, and statistics for its evaluation are named.

[Evolutionary changes in the NA and HA genes of H3N2 influenza virus in the Moscow Region during 2003-2009].

During the winter 2009 outbreak in the Moscow Region, H3N2 influenza viruses were isolated from the nasopharyngeal washes of patients via their propagation in the human intestinal (Caco-2) and bronchial (Calu-3) epithelial cell cultures maintaining the proteolytic cleavage of HA0--> HA1+HA2 and multicycle virus replication. Analysis of the nucleotide sequences of virus RNA indicated that the 2009 viruses differed from those isolated in 2003 in 14 and 21 amino acids of the neuraminidase (NA) and hemagglutinin (HA) genes, respectively. The NA gene was 1762 nucleotides long whereas the 2003 isolates had a deletion of 66 nucleotides (22 amino acids) in the stalk region (short-stalk NA genotype) of viruses.

[The dynamic characteristics of morbidity with temporary loss of work capacity in river fleet workers with digestive tract diseases before and after the accident at the Chernobyl Atomic Electric Power Station].

An analysis was done of morbidity involving temporary unfitness for work in those persons working on ships of the river fleet of the Kiev Water Transport Junction (KWTJ) and in the population of Ukraine. They had ulcer disease of the gastroduodenal location (UD), other gastrointestinal abnormalities in the upper portion of the tract. KWTJ workers demonstrated higher levels of UD morbidity as evidenced by the number of cases and by that of days of disability with almost equal duration of the case.