Biochim Biophys Acta Mol Basis Dis
April 2025
Progression of Prostatic Intra-epithelial Neoplasia (PIN) to Prostate Cancer (PCa) is characterized by a long latency period. This presents several opportunities for intervention. G-Protein coupled Estrogen Receptor 1 (GPER1) has emerged as an attractive target in the field of oncology.
View Article and Find Full Text PDFBackground: Intestinal transplantation (ITx) has the highest rate of rejection among solid organ grafts. We aimed to study the pathophysiology of rejection after ITx but lacked a tool for assessing cellular responses within the graft. Therefore, we developed a novel mixed lymphocyte reaction (MLR) assay to investigate immune responses in the graft.
View Article and Find Full Text PDFObjective: The proposed review identifies and describes the extent of Tobacco Harm Reduction (THR) strategies in Pakistan. It also examines the awareness and understanding of these strategies among healthcare professionals and tobacco users in Pakistan.
Introduction: Tobacco consumption poses a significant threat to human health and is a leading cause of non-communicable diseases.
Case: Pediatric Morel-Lavallée lesions are infrequent and may present in atypical locations. A 3-year-old boy presented with a nontender, mobile, cystic swelling on the medial aspect of his left distal thigh, 2 weeks after a road traffic accident. The diagnosis was confirmed using 3D ultrasonography.
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