[Metabolic disturbances and ways of their pharmacological correction in acute poisoning with ethanol in patients with chronic alcoholism].

Aim: To study an influence of chronic alcoholism on the clinical course and severity of metabolic disturbances in patients with acute poisoning with ethanol and to improve the treatment.

Material And Methods: Authors examined 93 patients stratified into three groups (acute poisoning with ethanol in patients with chronic alcoholism, without chronic alcoholism and those treated with reamberin).

Results And Conclusion: The presence of chronic alcoholism significantly augmented metabolic disturbances and influenced the disturbance of oxygen-transport function and free-radical processes in patients with acute intoxication with ethanol.

[Genetic control of the tissue concentration of serotonin in mice].

Brain stem, stomach and blood serotonin contents were studied in inbred mice of eight strains. The serotonin level in brain and in peripheral tissue is genetically determined. There was no correlation between the serotonin levels of brain, blood and stomach.