Publications by authors named "S V Lourenco"
Article Synopsis
- The study focused on comparing oral lichen planus and related lesions due to their risk of becoming cancerous and the need to differentiate them from similar conditions.
- Researchers conducted a survey among patients to collect sociodemographic and clinical data, analyzing this information using statistical tests.
- The findings revealed distinct characteristics for each type of lesion, with lichen planus showing reticular patterns and the buccal mucosa being the most affected area, while proliferative verrucous leukoplakia was linked with significant epithelial dysplasia.
Women experience several systemic changes over all stages of life, many due to hormonal fluctuations. The sensation of dry mouth is the most common oral clinical symptom in women from climacteric period onwards, suggesting that sex hormones are important in maintaining salivary glands and oral homeostasis. Although the oral cavity is not conventional considered a target tissue for oestrogen, the extent to which salivary glands morphology and function are impacted by ageing and hormonal variations remain unknown.
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- * The research analyzed samples from three canine OMM cell lines and human melanoma cell lines, identifying a total of 500 mutated genes in dogs, including notable ones like EP300 and NOTCH1, with 82 mutations shared between dogs and humans.
- * These findings offer important insights for understanding the genetic landscape of OMMs and could lead to the development of new treatment options for both canine and human patients in the future.
Article Synopsis
- The review focuses on metabolomics methodology and how saliva can be used for diagnosing and predicting oral diseases.
- A search of studies highlighted 25 research papers on saliva metabolites, revealing targeted and untargeted analysis approaches, mainly in conditions like periodontal disease and oral cancer.
- Metabolomics is recognized as a powerful tool for improving tumor diagnosis and personalizing treatment plans while providing insights into an organism's biochemical responses to various changes.
B cells can have a wide range of pro- and anti- inflammatory functions. A subset of B cells called regulatory B cells (Bregs) can potently suppress immune responses. Bregs have been shown to maintain immune homeostasis and modulate inflammatory responses.
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