[Overlapping Phenotype: Left Ventricular non-Compaction and Hypertrophic Cardiomyopathy].

Aim To study the clinical course of the mixed phenotype (hypertrophic cardiomyopathy, HCMP, and left ventricular noncompaction, LVNC); to determine its genetic causes; and to evaluate incidence of cardiovascular complications (CVC) during the follow-up period.Material and methods In screening of 286 patients with HCMP, 8 of them (2.8 %; median age, 41.

Binuclear Purkinje neurons.

Until the end of the XX century binuclear neurons of Purkinje in rodents and the humans were a subject of casual finds. However already then it was noticed that such cells are in old and sick mammals more often. It is therefore assumed that the appearance of the second nucleus has a regenerative value - compensation age-related or pathogenic loss of Purkinje cells.

[Age-related changes of the brain].

The first morphological signs of aging of the brain are found in the white matter already at a young age (20-40 years), and later (40-50 years) in a gray matter. After the 40-50 years appear and in subsequently are becoming more pronounced functional manifestations of morphological changes: the weakening of sensory-motor and cognitive abilities. While in principle this dynamic of age-related changes is inevitable, the rate of their development to a large extent determined by the genetic characteristics and lifestyle of the individual.

[Regeneration of neurons].

Describes the development of ideas about the regeneration of neurons from the approval "neurons are not restored" to an avalanche stream of messages on neurogenesis. We analysing literature about four ways of neuron regeneration. 1--neurogenesis; 2--intracellular regeneration; 3--BMDC fusion with Purkinje neurons in transgenic experiment; 4--regional cortical cells fusion.