The influence of the low-rate ionizing radiation (0.055 Gy/min) at the doses of 0.1; 0.
View Article and Find Full Text PDFThe influence of ionizing radiation with low absorbed dose rate (55 mGy x min(-1)) in 1, 12 and 24 hours after irradiation in doses of 0.1; 0.5 and 1.
View Article and Find Full Text PDFThe investigations of the functional state of the antioxidant system in epithelial cells from rat small intestine in dynamics after X-ray irradiation (0.1; 0.5 and 1.
View Article and Find Full Text PDFUkr Biokhim Zh (1999)
December 2006
A current state of researches on mechanisms of ion homeostasis regulation in the specific conditions of the uncontrolled malignant tumor growth (mainly in carcinomas) concerning the contribution of Na+,K+-ATPase, plasma membrane and sarco(endo)plasmic reticulum Ca2+-ATPases has been reviewed. Particular attention has been focused on the molecular and biochemical links providing the redistribution of the transporting ATPases isozyme pattern for the regulatory requirements of the cell signaling pathways at stable proliferation and viability in malignancy.
View Article and Find Full Text PDFNa+,K(+)-ATPase activities in macroscopically unchanged mucosa (conditionally normal tissue) and human colorectal carcinoma (mainly low-grade and moderately differentiated adenocarcinomas) have been investigated. Microsomal fractions are similar by dimensions of the membrane fragments detected by photon correlation spectroscopy analysis. The activation optima under digitonin pretreatment of the membrane fractions differ significantly for Na+,K(+)-ATPase and concomitant Mg(2+)-ATPase activity, but are the same in conditionally normal and cancerous tissues.
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