Publications by authors named "S V Kakade"
Article Synopsis
- Buserelin acetate is used to lower estrogen levels for treating breast cancer, and a new RP-HPLC method was developed and validated using the analytical quality by design approach.
- The study identified critical method parameters, such as flow rate and buffer pH, which impact the retention time and peak area during analysis.
- A robust method was established with excellent accuracy and precision for Buserelin acetate analysis, and PLGA-based nanoparticles were created to study the drug's release over 48 hours using Korsmeyer-Peppas kinetics.
Article Synopsis
- Butylated Hydroxytoluene (BHT), commonly used as an antioxidant in food, causes cellular toxicity by inducing oxidative stress and increasing reactive oxygen and nitrogen species (ROS and RNS).
- The herbal compounds Boeravinone B (BB) and Chebulinic acid (CA), when combined, showed significant protective effects against BHT’s toxicity by reducing levels of ROS and RNS, as well as decreasing enzymes and markers associated with oxidative stress.
- The treatment with BB and CA effectively reduced apoptosis and autophagy in cells exposed to BHT, promoting cell growth and suggesting their potential use as therapeutic agents for conditions related to oxidative stress-induced liver damage.
Background: Population aging is an emerging global trend. Because of decreasing fertility rates and improved healthcare, the lifespan of elderly population increased. Consequently, proportion of elderly population is increasing at an alarming rate.
View Article and Find Full Text PDFBackground: Family support is one of the determinants of lifestyle habits and relevant health behavior for pregnancy outcomes. In India, the joint family system is still practiced. Due to education, urbanization, and industrialization, the family institution continues to play a central role in people's lives.
View Article and Find Full Text PDFThe ability of humans to perceive and differentiate kinesthetic sensory information significantly influences our daily activities and motor control. This study examines the impact of asynchronous bi-manual discrimination tasks compared to uni-manual discrimination tasks on kinesthetic perception. Our study aims to reveal the relationship between kinesthetic perception of haptic signals by examining perceptual thresholds in three different scenarios using (i) the dominant hand, (ii) the non-dominant hand, and (iii) both hands simultaneously to differentiate between two successive signals.
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