Publications by authors named "S V Ghadge"
Background: Pit and fissure sealants are the most commonly used preventive measure against caries in permanent molars. Advancements in dental materials have led to the development of hydrophilic sealants. However, their clinical efficacy must be evaluated and compared with that of conventional hydrophobic sealants.
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- - The study evaluated the safety and effectiveness of a booster dose of VLA15, an investigational Lyme disease vaccine, after previously completing the primary vaccination series, as Lyme borreliosis cases are on the rise and effective vaccines are lacking.
- - Conducted as a randomized, placebo-controlled trial, the research involved healthy adults aged 18-65 from five US centers, who received either 135 μg or 180 μg of VLA15 or placebo over an 18-month period before the booster was administered.
- - Results focused on assessing the booster dose's immunogenicity and safety, with monitoring conducted by impartial groups to ensure accurate data collection, and the study is registered and completed under ClinicalTrials.gov (NCT
Unlabelled: Activation of the CXCL12/CXCR4/ACKR3 axis is known to aid myocardial repair through ischemia-triggered hypoxia-inducible factor-1α (HIF-1α). To enhance the upregulation of HIF-1α, we administered roxadustat, a novel prolyl hydroxylase inhibitor (PHI) clinically approved by the European Medicines Agency 2021 for the treatment of renal anemia, with the purpose of improving LV function and attenuating ischemic cardiomyopathy.
Methods: We evaluated roxadustat's impact on HIF-1 stimulation, cardiac remodeling, and function after MI.
Unlabelled: Dentists have a wide variety of techniques available to them such as tell -show-do, relaxation, distraction, systematic desensitisation, modelling, audio analgesia, hypnosis, and behaviour rehearsal. There is no concrete research as systematic review and meta-analysis indicating which explains the most effective distraction technique.
Aim: To summarize effectiveness of audio and audio-visual (AV) distraction aids for management of pain and anxiety in children undergoing dental treatment.
This in vitro study aimed to evaluate and compare the microleakage of bioactive, ormocer, and conventional glass ionomer cement (GIC) restorative materials in primary molars. In this study, class V cavities were prepared on the buccal surface of 75 noncarious extracted primary molars. The teeth were then restored as per the groups assigned.
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