Metabolomics and metabolites in ischemic stroke.

Stroke is a major reason for disability and the second highest cause of death in the world. When a patient is admitted to a hospital, it is necessary to identify the type of stroke, and the likelihood for development of a recurrent stroke, vascular dementia, and depression. These factors could be determined using different biomarkers.

Spectroscopic characterization of composite lithium materials irradiated with high-temperature plasma.

High-temperature plasma irradiation of materials leads to significant modification of surface structure, growth of deposited composite films and surface layers with induced self-similar granularity on the scale from macroscales to nanoscale due to strong plasma-surface interaction. The aim of this study was to characterize lithium materials irradiated with high-temperature plasma in the T-10 tokamak and PLM device. The reactivity of lithium leads to reactions with impurities in the plasma and on the vessel.

Disabling phosphorylation at the homer ligand of the metabotropic glutamate receptor 5 alleviates complete Freund's adjuvant-induced inflammatory pain.

Metabotropic glutamate receptor 5 (mGluR5) has been reported to contribute to inflammatory pain. The intracellular C-terminal domain has a Homer-binding motif that can form an mGluR5/Homer complex. Phosphorylation of mGluR5 at the Homer binding domain enhances the mGluR5/Homer interaction and modulates intracellular signal transduction.